Wait, save that integrin!

Wait, save that integrin!

RNF169 flips the repair switch P oulsen et al. describe an enzyme that helps a cell determine which repair method to use on DNA double-strand breaks (DSBs). Unrepaired DSBs can incite genomic chaos, spurring sections of chromosomes to relocate or even vanish. To ensure that doesn’t happen, a cell wraps a molecular bandage around a DSB. Enzymes arrive at the injury and ubiquitylate the surroundi...

Buy or wait , that is the option

This paper reports the results from an experiment on two-unit sequential auctions with and without a buyer’s option. The demand for the two items is either decreasing, flat, or increasing. The 4 main auction institutions (firstprice, Dutch, second-price, English) are studied. Observed bidding behavior is studied both in the strategy space and the payoff space. In the strategy space, the experim...

No proof that predator culls save livestock, study claims.

INTERHEART: nine factors that could save your life.

No matter where you live, how old you are or what you look like, health researchers have recently discovered that 90% of the most common cardiovascular event, the first heart attack (myocardial infarction), can be attributed to nine modifiable risk factors. The risk factors include: cigarette smoking, an abnormal ratio of blood lipids, high blood pressure, diabetes, abdominal obesity, stress, a...

Superoxide dismutases: active sites that save, but a protein that kills.

Protection from oxidative damage is sufficiently important that biology has evolved three independent enzymes for hastening superoxide dismutation: the Cu- and Zn-containing superoxide dismutases (Cu,Zn-SODs), the SODs that are specific for Fe or Mn or function with either of the two (Fe-SODs, Mn-SODs or Fe/Mn-SODs), and the SODs that use Ni (Ni-SODs). Despite the overwhelming similarities betw...